EMD-53507

Single-particle
2.31 Å
EMD-53507
3D View Gallery
Deposition: 26/04/2025
Map released: 05/11/2025
Last modified: 05/11/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-53507
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9r1f summary report (pdf.gz) Map and 9r1f FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of human MATE1 in complex with metformin

EMD-53507

Single-particle
2.31 Å
EMD-53507
3D View Gallery
Deposition: 26/04/2025
Map released: 05/11/2025
Last modified: 05/11/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, synthetic construct
Sample: Human multidrug and toxin extrusion protein (MATE1) in complex with Fab and metformin
Fitted models: 9r1f

Deposition Authors: Romane K, Peteani G, Mukherjee S, Kowal J, Rossi L, Hou J, Kossiakoff A, Lemmin T, Locher KP
Structural basis of drug recognition by human MATE1 transporter.
Romane K, Peteani G, Mukherjee S, Kowal J, Rossi L, Hou J, Kossiakoff AA, Lemmin T, Locher KP
(2025) Nat Commun , 16 , 9444 - 9444
PUBMED: 41145429
DOI: doi:10.1038/s41467-025-64490-z
ISSN: 2041-1723