EMD-53259

Single-particle
2.9 Å
EMD-53259
3D View Gallery
Deposition: 25/03/2025
Map released: 18/02/2026
Last modified: 04/03/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-53259

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9qo8 summary report (pdf.gz) Map-9qo8 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Inward-open structure of human GABA transporter 3 bound to selective inhibitor SR-THAP

EMD-53259

Single-particle
2.9 Å
EMD-53259
3D View Gallery
Deposition: 25/03/2025
Map released: 18/02/2026
Last modified: 04/03/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Human GABA transporter 3 bound to selective inhibitor SR-THAP
Fitted models: 9qo8

Deposition Authors: Mortensen JS , Bavo F, Jensen MH , Pedersen APS , Storm JP, Pape T , Frolund B, Wellendorph P , Shahsavar A
Structural basis for selective inhibition of human GABA transporter GAT3.
Mortensen JS , Bavo F, Jensen MH , Pedersen APS , Storm JP, Pape T , Frolund B, Wellendorph P , Shahsavar A
(2026) Nat Commun , 17 , 1774 - 1774
PUBMED: 41611703
DOI: doi:10.1038/s41467-026-68479-0
ISSN: 2041-1723