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EMD-53081
Cryo-EM structure of human O-GlcNAcase
EMD-53081
Single-particle3.08 Å
Deposition: 10/03/2025Map released: 17/09/2025
Last modified: 15/10/2025
Sample Organism:
Trichoplax adhaerens,
Homo sapiens
Sample: O-GlcNAcase from Trichoplax Adhaerens (TaOGA)
Fitted models: 9qen
Deposition Authors: Basse Hansen S, Bartual SG, Yuan H
,
Raimi OG,
Gorelik A ,
Ferenbach AT,
Lytje K ,
Pedersen JS ,
Drace T,
Boesen T ,
van Aalten DMF
Sample: O-GlcNAcase from Trichoplax Adhaerens (TaOGA)
Fitted models: 9qen
Deposition Authors: Basse Hansen S, Bartual SG, Yuan H
,
Raimi OG,
Gorelik A ,
Ferenbach AT,
Lytje K ,
Pedersen JS ,
Drace T,
Boesen T ,
van Aalten DMF
Multi-domain O-GlcNAcase structures reveal allosteric regulatory mechanisms.
Hansen SB ,
Bartual SG,
Yuan H ,
Raimi OG,
Gorelik A ,
Ferenbach AT,
Lytje K ,
Pedersen JS ,
Drace T,
Boesen T ,
van Aalten DMF
(2025) Nat Commun , 16 , 8828 - 8828
,
Bartual SG,
Yuan H ,
Raimi OG,
Gorelik A ,
Ferenbach AT,
Lytje K ,
Pedersen JS ,
Drace T,
Boesen T ,
van Aalten DMF
(2025) Nat Commun , 16 , 8828 - 8828
Grant Support:
- Wellcome Trust: 110061 (United Kingdom)
- Novo Nordisk Foundation: NNF21OC0065969 (Denmark)