EMD-53008

Single-particle
3.0 Å
EMD-53008
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Deposition: 04/03/2025
Map released: 17/12/2025
Last modified: 24/12/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-53008
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Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
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Activated XauSPARDA filament assembly with bound dsDNA substrate

EMD-53008

Single-particle
3.0 Å
EMD-53008
3D View Gallery
Deposition: 04/03/2025
Map released: 17/12/2025
Last modified: 24/12/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Xanthobacter autotrophicus Py2, Escherichia coli
Sample: Filament assembly of activated XauSPARDA binary monomers in the presence of dsDNA substrate
Fitted models: 9qcc

Deposition Authors: Manakova EN, Zaremba M , Jurgelaitis E
Activation of the SPARDA defense system by filament assembly using a beta-relay signaling mechanism widespread in prokaryotic Argonautes.
Jurgelaitis E, Zagorskaite E, Kopustas A, Asmontas S, Manakova E, Dalgediene I , Tylenyte U , Silanskas A, Toliusis P , Grybauskas A , Tutkus M , Venclovas C, Zaremba M
(2025) Cell Res , 35 , 1056 - 1078
PUBMED: 41298897
DOI: doi:10.1038/s41422-025-01198-1
ISSN: 1001-0602
Grant Support: