EMD-52999

Single-particle
3.77 Å
EMD-52999
3D View Gallery
Deposition: 02/03/2025
Map released: 13/08/2025
Last modified: 13/08/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-52999

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9qbh summary report (pdf.gz) Map-9qbh FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

HER2/ErbB2 extracellular domain (ECD) from a near full-length construct solubilized in amphipols.

EMD-52999

Single-particle
3.77 Å
EMD-52999
3D View Gallery
Deposition: 02/03/2025
Map released: 13/08/2025
Last modified: 13/08/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Aequorea victoria
Sample: HER2/ErbB2 extracellular domain (ECD) from a near full-length construct solubilized in amphipols.
Fitted models: 9qbh

Deposition Authors: Gragera M , Buschiazzo A , Vacca S
Structural analysis of HER2-trastuzumab complex reveals receptor conformational adaptation.
Vacca S , Gragera M , Buschiazzo A , Herreros D , Krieger JM , Bonn-Garcia S , Melero R , Sorzano CO, Carazo JM , Medalia O , Pluckthun A
(2025) Sci Adv , 11 , eadu9945 - eadu9945
PUBMED: 40712014
DOI: doi:10.1126/sciadv.adu9945
ISSN: 2375-2548