EMD-52704

Single-particle
2.98 Å
EMD-52704
3D View Gallery
Deposition: 04/02/2025
Map released: 05/03/2025
Last modified: 26/03/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-52704

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9i81 summary report (pdf.gz) Map-9i81 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

SARS-CoV-2 RdRp bound to a stack of three HeE1-2Tyr molecules

EMD-52704

Single-particle
2.98 Å
EMD-52704
3D View Gallery
Deposition: 04/02/2025
Map released: 05/03/2025
Last modified: 26/03/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Severe acute respiratory syndrome coronavirus 2
Sample: Coexpressed SARS-CoV-2 RdRp in the presence of 50 uM HeE1-2Tyr
Fitted models: 9i81

Deposition Authors: Kabinger F , Doze V, Schmitzova J, Lidschreiber M, Dienemann C, Cramer P
Structural basis of SARS-CoV-2 polymerase inhibition by nonnucleoside inhibitor HeE1-2Tyr.
Kabinger F , Doze V, Schmitzova J, Lidschreiber M, Dienemann C, Cramer P
(2025) PNAS , 122 , e2419854122 - e2419854122
PUBMED: 40035759
DOI: doi:10.1073/pnas.2419854122
ISSN: 1091-6490
ASTM: PNASA6
Grant Support: