EMD-52607

Single-particle
4.3 Å
EMD-52607
3D View Gallery
Deposition: 23/01/2025
Map released: 29/04/2026
Last modified: 29/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-52607

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

3D reconstruction of Themis:Grb2:ProMacrobody256 after 3D classification (Class 4)

EMD-52607

Single-particle
4.3 Å
EMD-52607
3D View Gallery
Deposition: 23/01/2025
Map released: 29/04/2026
Last modified: 29/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, synthetic construct
Sample: Themis-Grb2 complex bound to ProMacrobody 256

Deposition Authors: Clancy DM, Felix J, Bloch Y, Savvides SN
Structural and mechanistic insights into the constitutive Themis-Grb2 complex in T cell signalling.
Clancy DM, Sanz-Sanjuan A, Gilis E, Tougaard P, Velghe I, Van Droogenbroeck Y, Felix J, Bloch Y, Cuadrado AF, Merceron R, Schenck S, Vandenabeele P, Brunner JD, Taghon T, Elewaut D, Savvides SN
(2026) Nat Commun , 17
PUBMED: 42161968
DOI: doi:10.1038/s41467-026-73359-8
ISSN: 2041-1723