Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

EMD-52570

Single-particle
4.5 Å
EMD-52570
3D View Gallery
Deposition: 16/01/2025
Map released: 10/12/2025
Last modified: 10/12/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-52570
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9i1i summary report (pdf.gz) Map and 9i1i FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of mouse RNF213 (WB3/WB4 + ATP)

EMD-52570

Single-particle
4.5 Å
EMD-52570
3D View Gallery
Deposition: 16/01/2025
Map released: 10/12/2025
Last modified: 10/12/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Mus musculus
Sample: RNF213
Fitted models: 9i1i

Deposition Authors: Grabarczyk DB , Ahel J , Clausen T
ATP functions as a pathogen-associated molecular pattern to activate the E3 ubiquitin ligase RNF213.
Ahel J , Balci A , Faas V, Grabarczyk DB , Harmo R , Squair DR, Zhang J, Roitinger E , Lamoliatte F, Mathur S, Deszcz L, Bell LE , Lehner A, Williams TL, Sowar H, Meinhart A, Wood NT , Clausen T , Virdee S , Fletcher AJ
(2025) Nat Commun , 16 , 4414 - 4414
PUBMED: 40360510
DOI: doi:10.1038/s41467-025-59444-4
ISSN: 2041-1723
Grant Support: