EMD-52227

Single-particle
3.16 Å
EMD-52227
3D View Gallery
Deposition: 02/12/2024
Map released: 09/07/2025
Last modified: 16/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-52227

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9hju summary report (pdf.gz) Map-9hju FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Structure of 2x Zincore (SEPHS1:QRICH1) binding to ZFP91 on DNA

EMD-52227

Single-particle
3.16 Å
EMD-52227
3D View Gallery
Deposition: 02/12/2024
Map released: 09/07/2025
Last modified: 16/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Dual Zincore Complex
Fitted models: 9hju

Deposition Authors: Borza R , Perrakis A
Zincore, an atypical coregulator, binds zinc finger transcription factors to control gene expression.
Bianchi D , Borza R , De Zan E , Huelsz-Prince G, Gregoricchio S , Dekker M, Fish A , Mazouzi A , Kroese LJ, Linder S , Hernandez-Quiles M, Vermeulen M , Celie PHN , Krimpenfort P, Song JY , Zwart W, Wessels L , Nijman SMB , Perrakis A , Brummelkamp TR
(2025) Science , 389 , eadv2861 - eadv2861
PUBMED: 40608935
DOI: doi:10.1126/science.adv2861
ISSN: 1095-9203
ASTM: SCIEAS
Grant Support: