EMD-51978

Single-particle
3.08 Å
EMD-51978 Deposition: 01/11/2024
Map released: 22/01/2025
Last modified: 22/01/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-51978

mature 50S subunit supplemented with Api137

EMD-51978

Single-particle
3.08 Å
EMD-51978 Deposition: 01/11/2024
Map released: 22/01/2025
Last modified: 22/01/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Escherichia coli, Apis mellifera
Sample: pre50S precursor derived from Api137-treated cells supplemented with Api137
Fitted models: 9ha6

Deposition Authors: Lauer S, Nikolay R , Spahn CMT
The proline-rich antimicrobial peptide Api137 disrupts large ribosomal subunit assembly and induces misfolding.
Lauer SM , Gasse J , Krizsan A, Reepmeyer M , Sprink T, Nikolay R , Spahn CMT , Hoffmann R
(2025) Nat Commun , 16 , 567 - 567
PUBMED: 39794318
DOI: doi:10.1038/s41467-025-55836-8
ISSN: 2041-1723