EMD-51730

Helical reconstruction
2.9 Å
EMD-51730
3D View Gallery
Deposition: 04/10/2024
Map released: 05/03/2025
Last modified: 16/04/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-51730

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9gzp summary report (pdf.gz) Map-9gzp FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

WT-IAPP cryo-EM structure Type LL - control reaction

EMD-51730

Helical reconstruction
2.9 Å
EMD-51730
3D View Gallery
Deposition: 04/10/2024
Map released: 05/03/2025
Last modified: 16/04/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: synthetic construct, Homo sapiens
Sample: Amyloid fibril with helical symmetry
Fitted models: 9gzp

Deposition Authors: Wilkinson M, Taylor AIP , Xu Y, Chakraborty P , Brinkworth A, Willis LF, Zhuravleva A , Ranson NA, Foster R , Radford SE
Kinetic Steering of Amyloid Formation and Polymorphism by Canagliflozin, a Type-2 Diabetes Drug.
Taylor AIP , Xu Y, Wilkinson M, Chakraborty P , Brinkworth A, Willis LF, Zhuravleva A , Ranson NA, Foster R , Radford SE
(2025) J Am Chem Soc , 147 , 11859 - 11878
PUBMED: 39985130
DOI: doi:10.1021/jacs.4c16743
ISSN: 1520-5126
ASTM: JACSAT
Grant Support: