EMD-51109

Single-particle
2.75 Å
EMD-51109
3D View Gallery
Deposition: 19/07/2024
Map released: 04/06/2025
Last modified: 09/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-51109
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9g74 summary report (pdf.gz) Map and 9g74 FULL report (pdf.gz)
EMICSS annotations (xml)

Mouse mitochondrial DNA polymerase gamma ternary complex in replication conformer

EMD-51109

Single-particle
2.75 Å
EMD-51109
3D View Gallery
Deposition: 19/07/2024
Map released: 04/06/2025
Last modified: 09/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Mus musculus, synthetic construct
Sample: Mouse mitochondrial DNA polymerase gamma ternary complex in replication conformer
Fitted models: 9g74

Deposition Authors: Valenzuela S , Falkenberg M
Modelling POLG mutations in mice unravels a critical role of POL gamma Beta in regulating phenotypic severity.
Corra S, Zuppardo A , Valenzuela S , Jenninger L, Cerutti R, Sillamaa S , Hoberg E, Johansson KAS , Rovsnik U, Volta S, Silva-Pinheiro P , Davis H, Trifunovic A , Minczuk M , Gustafsson CM , Suomalainen A , Zeviani M, Macao B , Zhu X , Falkenberg M , Viscomi C
(2025) Nat Commun , 16 , 4782 - 4782
PUBMED: 40404629
DOI: doi:10.1038/s41467-025-60059-y
ISSN: 2041-1723
Grant Support: