EMD-50888

Helical reconstruction
2.23 Å
EMD-50888
3D View Gallery
Deposition: 03/07/2024
Map released: 17/07/2024
Last modified: 22/01/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-50888

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9fyp summary report (pdf.gz) Map-9fyp FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo EM structure of the type 3B polymorph of alpha-synuclein at low pH.

EMD-50888

Helical reconstruction
2.23 Å
EMD-50888
3D View Gallery
Deposition: 03/07/2024
Map released: 17/07/2024
Last modified: 22/01/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: alpha-synuclein amyloid fibril
Fitted models: 9fyp

Deposition Authors: Frey L, Qureshi BM, Kwiatkowski W, Rhyner D, Greenwald J , Riek R
On the pH-dependence of alpha-synuclein amyloid polymorphism and the role of secondary nucleation in seed-based amyloid propagation.
Frey L, Ghosh D, Qureshi BM, Rhyner D, Guerrero-Ferreira R, Pokharna A , Kwiatkowski W, Serdiuk T, Picotti P , Riek R, Greenwald J
(2024) eLife , 12
PUBMED: 39196271
DOI: doi:10.7554/eLife.93562
ISSN: 2050-084X
Grant Support: