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EMD-50181

Single-particle
3.27 Å
EMD-50181
3D View Gallery
Deposition: 26/04/2024
Map released: 14/08/2024
Last modified: 28/08/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-50181
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9f42 summary report (pdf.gz) Map and 9f42 FULL report (pdf.gz)
EMICSS annotations (xml)

cryo-EM structure of LST2 TOS peptide bound to human mTOR complex 1, focused on RAPTOR

EMD-50181

Single-particle
3.27 Å
EMD-50181
3D View Gallery
Deposition: 26/04/2024
Map released: 14/08/2024
Last modified: 28/08/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: mTORC1 in complex with synthesised LST2 TOS peptide
Fitted models: 9f42

Deposition Authors: Craigie LM , Maier T
mTORC1 phosphorylates and stabilizes LST2 to negatively regulate EGFR.
Battaglioni S , Craigie LM , Filippini S , Maier T , Hall MN
(2024) PNAS , 121 , e2405959121 - e2405959121
PUBMED: 39141345
DOI: doi:10.1073/pnas.2405959121
ISSN: 1091-6490
ASTM: PNASA6