EMD-50034

Single-particle
3.2 Å
EMD-50034
3D View Gallery
Deposition: 05/04/2024
Map released: 22/01/2025
Last modified: 16/04/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-50034
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9exa summary report (pdf.gz) Map and 9exa FULL report (pdf.gz)
EMICSS annotations (xml)

SARS-CoV-2 M protein dimer (short form) in complex with Fab-B and CIM-834

EMD-50034

Single-particle
3.2 Å
EMD-50034
3D View Gallery
Deposition: 05/04/2024
Map released: 22/01/2025
Last modified: 16/04/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Severe acute respiratory syndrome coronavirus 2, Mus musculus
Sample: SARS-CoV-2 M protein dimer (short form) in complex with Fab-B and CIM-834
Fitted models: 9exa

Deposition Authors: Debski-Antoniak OJ, Hurdiss DL
A coronavirus assembly inhibitor that targets the viral membrane protein.
Laporte M , Jochmans D , Bardiot D, Desmarets L , Debski-Antoniak OJ, Mizzon G , Abdelnabi R , Leyssen P , Chiu W , Zhang Z, Nomura N , Boland S, Ohto U , Stahl Y , Wuyts J, De Jonghe S , Stevaert A , van Hemert MJ, Bontes BW , Wanningen P, Groenewold GJM , Zegar A , Owczarek K , Joshi S, Koukni M, Arzel P, Klaassen H, Vanherck JC, Vandecaetsbeek I, Cremers N , Donckers K, Francken T, Van Buyten T, Rymenants J , Schepers J, Pyrc K , Hilgenfeld R, Dubuisson J , Bosch BJ , Van Kuppeveld F, Eydoux C , Decroly E , Canard B, Naesens L , Weynand B , Snijder EJ , Belouzard S , Shimizu T , Bartenschlager R , Hurdiss DL , Marchand A, Chaltin P, Neyts J
(2025) Nature , 640 , 514 - 523
PUBMED: 40140569
DOI: doi:10.1038/s41586-025-08773-x
ISSN: 1476-4687
ASTM: NATUAS