EMD-49992

Single-particle
3.5 Å
EMD-49992
3D View Gallery
Deposition: 02/04/2025
Map released: 21/01/2026
Last modified: 05/08/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-49992

Archive Files (Depositor)

Primary 3D volume (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9o0l summary report (pdf.gz) Map-9o0l FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

CryoEM structure of the CCDC6-PP2Ac multimer

EMD-49992

Single-particle
3.5 Å
EMD-49992
3D View Gallery
Deposition: 02/04/2025
Map released: 21/01/2026
Last modified: 05/08/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Complex of FBXO42-CCDC6-PP2Ac
Fitted models: 9o0l

Deposition Authors: Hsu PL , Michaelian N , Azumaya C, Coassolo S, Yauch RL
Template-driven scaffolding of SCF FBXO42 regulates PP2A degradation.
Coassolo S, Michaelian N , Maculins T , Azumaya CM , Cheung TK, Yin J, Zilberleyb I, Pahuja KB, Garner T, Lau T, Mau D , Grimmer M, Fortin JP, Costa M, Dimitrova YN, Rose CM, Hsu PL , Yauch RL
(2026) Nature , 654 , 250 - 260
PUBMED: 41986709
DOI: doi:10.1038/s41586-026-10368-z
ISSN: 1476-4687
ASTM: NATUAS
Grant Support: