EMD-49966

Single-particle
3.2 Å
EMD-49966
3D View Gallery
Deposition: 02/04/2025
Map released: 21/01/2026
Last modified: 17/06/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-49966

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9o04 summary report (pdf.gz) Map-9o04 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

CryoEM structure of the FBXO42-CCDC6-PP2Ac degradasome

EMD-49966

Single-particle
3.2 Å
EMD-49966
3D View Gallery
Deposition: 02/04/2025
Map released: 21/01/2026
Last modified: 17/06/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Complex of FBXO42-CCDC6-PP2Ac
Fitted models: 9o04

Deposition Authors: Hsu PL, Michaelian N, Azumaya C, Coassolo S, Yauch RL
Template-driven scaffolding of SCF FBXO42 regulates PP2A degradation.
Coassolo S, Michaelian N, Maculins T, Azumaya CM, Cheung TK, Yin J, Zilberleyb I, Pahuja KB, Garner T, Lau T, Mau D, Grimmer M, Fortin JP, Costa M, Dimitrova YN, Rose CM, Hsu PL, Yauch RL
(2026) Nature , 654 , 250 - 260
PUBMED: 41986709
DOI: doi:10.1038/s41586-026-10368-z
ISSN: 1476-4687
ASTM: NATUAS
Grant Support: