EMD-49898

Single-particle
3.1 Å
EMD-49898
3D View Gallery
Deposition: 25/03/2025
Map released: 04/02/2026
Last modified: 25/03/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-49898

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9nx1 summary report (pdf.gz) Map-9nx1 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Alpha7-nicotinic acetylcholine receptor bound to conotoxin ImII

EMD-49898

Single-particle
3.1 Å
EMD-49898
3D View Gallery
Deposition: 25/03/2025
Map released: 04/02/2026
Last modified: 25/03/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Conus imperialis
Sample: Complex of conotoxin ImII and human Alpha7 nicotinic Acetylcholine receptor
Fitted models: 9nx1

Deposition Authors: Stowell MHB, Hibbs RE, Noviello CM, Bhattacharjee B
Shape-shifting conotoxins reveal divergent pore-targeting mechanisms in nicotinic receptors.
Bhattacharjee B, Noviello CM, Rahman MM, Mayer JP, Gajewiak J, McIntosh JM, Hibbs RE, Stowell MHB
(2026) Structure , 34 , 463
PUBMED: 41468893
DOI: doi:10.1016/j.str.2025.12.003
ISSN: 0969-2126
ASTM: STRUE6