EMD-49892
Cryo-EM structure of DDB1dB:CRBN:mezigdomide:SALL4(392-449)
EMD-49892
Single-particle2.7 Å
Deposition: 24/03/2025Map released: 04/02/2026
Last modified: 04/02/2026
Sample Organism:
Homo sapiens
Sample: Ternary complex of DDB1dB:CRBN:mezigdomide:SALL4(392-449)
Fitted models: 9nws
Deposition Authors: Park J, Hunkeler M, Roy Burman SS
,
Fishcer ES
Sample: Ternary complex of DDB1dB:CRBN:mezigdomide:SALL4(392-449)
Fitted models: 9nws
Deposition Authors: Park J, Hunkeler M, Roy Burman SS
,
Fishcer ES
Expanding the druggable zinc-finger proteome defines properties of drug-induced degradation.
Slabicki M,
Park J,
Nowak RP,
Roy Burman SS ,
Pellman J,
Zou C,
Razumkov H,
Carreiro J,
Rastogi S,
Goldstein A,
Nagiec MM,
Donovan KA,
Che J,
Hunkeler M,
Geng Q ,
Hsu CL,
Lakshminarayan M,
Shu C,
Zon RL,
Kozicka Z ,
Park PMC,
Tsai JM,
Yoon H,
Jones LH ,
Sperling AS ,
Gray NS ,
Fischer ES,
Ebert BL
(2025) Mol Cell , 85 , 3184 - 3201.e14
,
Pellman J,
Zou C,
Razumkov H,
Carreiro J,
Rastogi S,
Goldstein A,
Nagiec MM,
Donovan KA,
Che J,
Hunkeler M,
Geng Q ,
Hsu CL,
Lakshminarayan M,
Shu C,
Zon RL,
Kozicka Z ,
Park PMC,
Tsai JM,
Yoon H,
Jones LH ,
Sperling AS ,
Gray NS ,
Fischer ES,
Ebert BL
(2025) Mol Cell , 85 , 3184 - 3201.e14
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