EMD-49735

Single-particle
3.4 Å
EMD-49735
3D View Gallery
Deposition: 14/03/2025
Map released: 15/10/2025
Last modified: 11/03/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-49735

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9nrj summary report (pdf.gz) Map-9nrj FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

abTCR bound to SAR444200, a novel anti-GPC3 T-cell engager, for the treatment of GPC3+ solid tumors

EMD-49735

Single-particle
3.4 Å
EMD-49735
3D View Gallery
Deposition: 14/03/2025
Map released: 15/10/2025
Last modified: 11/03/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: TCRab
Fitted models: 9nrj

Deposition Authors: Svidritskiy E , Qiu Y , Yanfeng Z
Identification and Nonclinical Characterization of SAR444200, a Novel Anti-GPC3 NANOBODY T-cell Engager, for the Treatment of GPC3+ Solid Tumors.
Meoni P , Vintem APB , Cortez-Retamozo VF , Jacobs J , De Tavernier E , Fiorentini P , Van Hoorick D , Batchelor JD , Svidritskiy E , Qiu Y , Dejonckheere E , Li A , Pao LI , Buyse MA
(2026) Mol.Cancer Ther. , 25 , 361 - 370
PUBMED: 41041827
DOI: doi:10.1158/1535-7163.MCT-24-1049
ISSN: 1538-8514
Grant Support: