EMD-49708
cryo-EM structure of broad betacoronavirus binding antibody 1871 in complex with OC43 S2 subunit
EMD-49708
Single-particle2.6 Å
Deposition: 13/03/2025Map released: 12/11/2025
Last modified: 31/12/2025
Sample Organism:
Homo sapiens,
Human coronavirus OC43
Sample: OC43 S2 subunit complex with Fab 1871
Fitted models: 9nqz
Deposition Authors: Muthuraman K
,
Jackman MJ,
Julien JP
Sample: OC43 S2 subunit complex with Fab 1871
Fitted models: 9nqz
Deposition Authors: Muthuraman K
,
Jackman MJ,
Julien JP
Human antibody targeting of coronavirus spike S2 subunit is associated with protection mediated by Fc effector functions.
Muthuraman K ,
Jackman M,
Liang Y,
Garrett ME,
Cui H,
Nguyen LVH,
Ivanochko D,
Ye C ,
Pino PA,
Hicks A,
Maingot B,
Yusko E,
Benzeno S,
Martinez-Sobrido L ,
Torrelles JB,
Gilbert AE,
Rubin BER,
Keitany G,
Jetha A,
Julien J-P
(2025) J Virol , 99 , e0152325 - e0152325
,
Jackman M,
Liang Y,
Garrett ME,
Cui H,
Nguyen LVH,
Ivanochko D,
Ye C ,
Pino PA,
Hicks A,
Maingot B,
Yusko E,
Benzeno S,
Martinez-Sobrido L ,
Torrelles JB,
Gilbert AE,
Rubin BER,
Keitany G,
Jetha A,
Julien J-P
(2025) J Virol , 99 , e0152325 - e0152325
Grant Support:
- Bill & Melinda Gates Foundation: INV-023398 (United States)