EMD-49646

Single-particle
2.97 Å
EMD-49646
3D View Gallery
Deposition: 12/03/2025
Map released: 19/11/2025
Last modified: 19/11/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-49646

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9nq9 summary report (pdf.gz) Map-9nq9 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Magnesium ions-bound closed-state cryo-EM structure of human TRPV6 in cNW11 nanodiscs

EMD-49646

Single-particle
2.97 Å
EMD-49646
3D View Gallery
Deposition: 12/03/2025
Map released: 19/11/2025
Last modified: 19/11/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: sample 1
Fitted models: 9nq9

Deposition Authors: Neuberger A , Sobolevsky AI
The locking mechanism of human TRPV6 inhibition by intracellular magnesium.
Neuberger A , Shalygin A, Veretenenko II , Trofimov YA , Gudermann T , Chubanov V , Efremov RG , Sobolevsky AI
(2025) Nat Commun , 16 , 9826 - 9826
PUBMED: 41198662
DOI: doi:10.1038/s41467-025-65919-1
ISSN: 2041-1723