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EMD-49635

Single-particle
2.1 Å
EMD-49635
3D View Gallery
Deposition: 11/03/2025
Map released: 11/06/2025
Last modified: 30/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-49635
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9npx summary report (pdf.gz) Map and 9npx FULL report (pdf.gz)
EMICSS annotations (xml)

SARS-CoV-2 nsp1 bound to the Rhinolophus lepidus 40S ribosomal subunit (local refinement of the 40S body)

EMD-49635

Single-particle
2.1 Å
EMD-49635
3D View Gallery
Deposition: 11/03/2025
Map released: 11/06/2025
Last modified: 30/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Rhinolophus lepidus, Severe acute respiratory syndrome coronavirus 2, Homo sapiens
Sample: SARS-CoV-2 nsp1 bound Rhinolophus lepidus 40S ribosomal subunit
Fitted models: 9npx

Deposition Authors: Gen R, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler D
SARS-CoV-2 nsp1 mediates broad inhibition of translation in mammals.
Gen R, Addetia A, Asarnow D, Park YJ, Quispe J, Chan MC, Brown JT, Lee J, Campbell MG, Lapointe CP, Veesler D
(2025) Cell Rep , 44 , 115696 - 115696
PUBMED: 40359110
DOI: doi:10.1016/j.celrep.2025.115696
ISSN: 2211-1247
Grant Support: