EMD-49521

Single-particle
3.53 Å
EMD-49521
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Deposition: 03/03/2025
Map released: 07/05/2025
Last modified: 21/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-49521
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9nlp summary report (pdf.gz) Map and 9nlp FULL report (pdf.gz)
EMICSS annotations (xml)

HIV-1 Reverse Transcriptase with New Non-Nucleoside Reverse Transcriptase Inhibitor 12126065

EMD-49521

Single-particle
3.53 Å
EMD-49521
3D View Gallery
Deposition: 03/03/2025
Map released: 07/05/2025
Last modified: 21/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: HIV-1 06TG.HT008
Sample: HIV-1 reverse transcriptase with novel inhibitor
Fitted models: 9nlp

Deposition Authors: Young MA, Lane TR , Raman R, Nelson JAE, Riabova O, Kazakova E, Monakhova N, Tsedilin A, Rees SD , Quinnell D, Chang G, Ekins S
Cryo-EM Structure of HIV-1 Reverse Transcriptase with N -Phenyl-1-(phenylsulfonyl)-1 H -1,2,4-triazol-3-amine: A New HIV-1 Non-nucleoside Inhibitor.
Young MA, Lane TR , Raman R, Nelson JAE, Riabova O, Kazakova E, Monakhova N, Tsedilin A, Rees SD , Quinnell D, Makarov V, Chang G, Ekins S
(2025) Acs Infect Dis. , 11 , 1257 - 1267
PUBMED: 40304150
DOI: doi:10.1021/acsinfecdis.5c00189
ISSN: 2373-8227
Grant Support: