EMD-49409

Single-particle
4.1 Å
EMD-49409
3D View Gallery
Deposition: 24/02/2025
Map released: 17/09/2025
Last modified: 01/10/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-49409

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9nhd summary report (pdf.gz) Map-9nhd FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of SIWI-piRNA-target(49-nt)-GTSF1-Maelstrom complex (conformation 2)

EMD-49409

Single-particle
4.1 Å
EMD-49409
3D View Gallery
Deposition: 24/02/2025
Map released: 17/09/2025
Last modified: 01/10/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Bombyx mori, synthetic construct
Sample: SIWI-piRNA-target(49-nt)-GTSF1-Maelstrom complex (conformation 2)
Fitted models: 9nhd

Deposition Authors: Sarkar S , Gebert LFR, MacRae IJ
A conserved PIWI silencing complex detects piRNA-target engagement.
De D, Sarkar S , Gebert LFR, Wiryaman T, Anzelon TA, MacRae IJ
(2025) Mol Cell , 85 , 3275 - 3287.e7
PUBMED: 40912244
DOI: doi:10.1016/j.molcel.2025.08.010
ISSN: 1097-2765
ASTM: MOCEFL