EMD-49405

Single-particle
3.02 Å
EMD-49405
3D View Gallery
Deposition: 24/02/2025
Map released: 12/11/2025
Last modified: 07/01/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-49405

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9nh7 summary report (pdf.gz) Map-9nh7 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

CryoEM Structure of De Novo VHH, VHH_flu_01, bound to influenza HA, strain A/USA:Iowa/1943 H1N1

EMD-49405

Single-particle
3.02 Å
EMD-49405
3D View Gallery
Deposition: 24/02/2025
Map released: 12/11/2025
Last modified: 07/01/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: synthetic construct, Influenza A virus (strain A/USA:Iowa/1943 H1N1)
Sample: De Novo VHH, VHH_flu_01, bound to influenza HA, strain A/USA:Iowa/1943 H1N1.
Fitted models: 9nh7

Deposition Authors: Borst AJ, Weidle C
Atomically accurate de novo design of antibodies with RFdiffusion.
Bennett NR, Watson JL , Ragotte RJ, Borst AJ, See DL, Weidle C, Biswas R , Yu Y , Shrock EL, Ault R, Leung PJY , Huang B, Goreshnik I, Tam J, Carr KD , Singer B , Criswell C, Wicky BIM , Vafeados D , Garcia Sanchez M , Kim HM , Vazquez Torres S, Chan S , Sun SM , Spear TT, Sun Y, O'Reilly K , Maris JM , Sgourakis NG, Melnyk RA , Liu CC , Baker D
(2026) Nature , 649 , 183 - 193
PUBMED: 41193805
DOI: doi:10.1038/s41586-025-09721-5
ISSN: 1476-4687
ASTM: NATUAS