EMD-49302

Single-particle
3.88 Å
EMD-49302
3D View Gallery
Deposition: 19/02/2025
Map released: 04/06/2025
Last modified: 04/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-49302

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9ne9 summary report (pdf.gz) Map-9ne9 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Human polymerase epsilon bound to PCNA and DNA with a pre-existing mismatch in the blocked conformation I

EMD-49302

Single-particle
3.88 Å
EMD-49302
3D View Gallery
Deposition: 19/02/2025
Map released: 04/06/2025
Last modified: 04/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, synthetic construct
Sample: Ternary complex of human DNA polymerase epsilon with PCNA and the mismatched DNA
Fitted models: 9ne9

Deposition Authors: Wang F , He Q, Li H
The proofreading mechanism of the human leading-strand DNA polymerase epsilon holoenzyme.
Wang F , He Q, O'Donnell ME , Li H
(2025) PNAS , 122 , e2507232122 - e2507232122
PUBMED: 40440070
DOI: doi:10.1073/pnas.2507232122
ISSN: 1091-6490
ASTM: PNASA6