EMD-49277

Single-particle
3.8 Å
EMD-49277
3D View Gallery
Deposition: 18/02/2025
Map released: 13/08/2025
Last modified: 25/02/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-49277
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9ndt summary report (pdf.gz) Map and 9ndt FULL report (pdf.gz)
EMICSS annotations (xml)

The flexible portion of Cryo-EM structure of Herpesvirus Helicase-Primase complex prepared with forked DNA and ATP-gamma-S

EMD-49277

Single-particle
3.8 Å
EMD-49277
3D View Gallery
Deposition: 18/02/2025
Map released: 13/08/2025
Last modified: 25/02/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Herpesviridae
Sample: The ternary complex of HSV-1 helicase-primase complex of UL8/UL52/UL5
Fitted models: 9ndt

Deposition Authors: Yao Q , Yu X
Structural and mechanistic insights into herpesvirus helicase-primase and its therapeutic inhibitors.
Yao Q , Mercier A , Nayak A, May L, Ho PY, Lewis-Ballester A, Nair V , Sapre A, Aeschbacher T, Mukherjee J, Richards C , Mateo R, Cho A, Lansdon E , Yu X
(2025) Nat Microbiol , 10 , 3191 - 3201
PUBMED: 41188384
DOI: doi:10.1038/s41564-025-02168-4
ISSN: 2058-5276
Grant Support: