EMD-49130

Single-particle
3.22 Å
EMD-49130
3D View Gallery
Deposition: 08/02/2025
Map released: 04/02/2026
Last modified: 10/06/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-49130

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9n8j summary report (pdf.gz) Map-9n8j FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Stabilized tandem antigen chimera of Pfs230 and Pfs48/45 bound by potent mAbs

EMD-49130

Single-particle
3.22 Å
EMD-49130
3D View Gallery
Deposition: 08/02/2025
Map released: 04/02/2026
Last modified: 10/06/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Rattus, Plasmodium falciparum
Sample: Stabilized tandem antigen chimera of Pfs230 and Pfs48/45 bound by four potent mAbs
Fitted models: 9n8j

Deposition Authors: Hailemariam S, Ivanochko D, Julien JP
A stabilized tandem antigen chimera that elicits potent malaria transmission-reducing activity.
Ivanochko D, Miura K, Hailemariam S, Ravichandran R, Song Y, Huang WC, Stoter R, Teelen K, van Gemert GJ, Leaf EM, Chan S, Men C, Semesi A, Shiu C, MacGill RS, Long CA, Jore MM, King NP, Lovell JF, Julien JP
(2026) Nat Commun , 17
PUBMED: 41580424
DOI: doi:10.1038/s41467-026-68761-1
ISSN: 2041-1723