EMD-48984
Cryo-EM map of APC/C-CDC20-UBE2C-H3/H4 crosslinked complex
EMD-48984
Single-particle3.9 Å
Deposition: 04/02/2025Map released: 16/04/2025
Last modified: 16/04/2025
Sample Organism:
Homo sapiens
Sample: APC/C-CDC20-UBE2C-H2A/H2B crosslinked complex
Fitted models: 9n9s
Deposition Authors: Skrajna A
,
Bordrug T ,
Brown NG ,
McGinty RK
Sample: APC/C-CDC20-UBE2C-H2A/H2B crosslinked complex
Fitted models: 9n9s
Deposition Authors: Skrajna A
,
Bordrug T ,
Brown NG ,
McGinty RK
APC/C-mediated ubiquitylation of extranucleosomal histone complexes lacking canonical degrons.
Skrajna A ,
Bodrug T,
Martinez-Chacin RC,
Fisher CB,
Welsh KA ,
Simmons HC ,
Arteaga EC,
Simmons JM ,
Nasr MA ,
LaPak KM,
Nguyen A,
Huynh MT,
Fargo I ,
Welfare JG,
Zhao Y ,
Lawrence DS ,
Goldfarb D ,
Brown NG ,
McGinty RK
(2025) Nat Commun , 16 , 2561 - 2561
,
Bodrug T,
Martinez-Chacin RC,
Fisher CB,
Welsh KA ,
Simmons HC ,
Arteaga EC,
Simmons JM ,
Nasr MA ,
LaPak KM,
Nguyen A,
Huynh MT,
Fargo I ,
Welfare JG,
Zhao Y ,
Lawrence DS ,
Goldfarb D ,
Brown NG ,
McGinty RK
(2025) Nat Commun , 16 , 2561 - 2561
Grant Support:
- National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): R35GM133498 (United States)
- National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): R35GM128855 (United States)
- National Science Foundation (NSF, United States): DGE-1650116 (United States)
- American Cancer Society: 132609-PF-18-153-01-DMC (United States)