EMD-48494

Single-particle
3.16 Å
EMD-48494
3D View Gallery
Deposition: 29/12/2024
Map released: 08/10/2025
Last modified: 04/02/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-48494

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

The "up" state cryo-EM map of nucleosome-bound DNA methyltransferases DNMT3A2 and DNMT3L

EMD-48494

Single-particle
3.16 Å
EMD-48494
3D View Gallery
Deposition: 29/12/2024
Map released: 08/10/2025
Last modified: 04/02/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Xenopus laevis
Sample: Nucleosome-bound DNA methyltransferases DNMT3A2 and DNMT3L

Deposition Authors: Yan Y , Zhou XE , Xu TH
Mechanisms of DNMT3A-3L-mediated de novo DNA methylation on chromatin.
Yan Y , Zhou XE , Thomas SL , Liu M , Lai GQ, Worden EJ , Jones PA , Xu TH
(2026) Nat Struct Mol Biol , 33 , 171 - 183
PUBMED: 41174279
DOI: doi:10.1038/s41594-025-01704-4
ISSN: 1545-9985