EMD-48401

Single-particle
3.9 Å
EMD-48401
3D View Gallery
Deposition: 20/12/2024
Map released: 10/09/2025
Last modified: 08/10/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-48401

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9mmr summary report (pdf.gz) Map-9mmr FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of CRAF/MEK1/14-3-3 complex (open monomer conformation, CRAF Y340D/Y341D mutant)

EMD-48401

Single-particle
3.9 Å
EMD-48401
3D View Gallery
Deposition: 20/12/2024
Map released: 10/09/2025
Last modified: 08/10/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Spodoptera exigua
Sample: CRAF/MEK1/14-3-3 complex
Fitted models: 9mmr

Deposition Authors: Jang DM , Jeon H, Eck MJ
Cryo-EM structures of CRAF/MEK1/14-3-3 complexes in autoinhibited and open-monomer states reveal features of RAF regulation.
Jang DM , Boxer K , Ha BH, Tkacik E, Levitz T, Rawson S , Metivier RJ, Schmoker A , Jeon H, Eck MJ
(2025) Nat Commun , 16 , 8150 - 8150
PUBMED: 40890113
DOI: doi:10.1038/s41467-025-63227-2
ISSN: 2041-1723