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EMD-47700
ACKR3 phosphorylated by GRK5 in complex with arrestin2 and Fab7
EMD-47700
Single-particle3.4 Å
Deposition: 04/11/2024Map released: 02/04/2025
Last modified: 15/10/2025
Sample Organism:
Bos taurus,
Homo sapiens,
synthetic construct
Sample: human ACKR3 phosphorylated by GRK5 in complex with Arrestin3
Fitted models: 9e82
Deposition Authors: Chen Q
,
Fuller J
,
Tesmer JJG
Sample: human ACKR3 phosphorylated by GRK5 in complex with Arrestin3
Fitted models: 9e82
Deposition Authors: Chen Q
,
Fuller J
,
Tesmer JJG
Effect of phosphorylation barcodes on arrestin binding to a chemokine receptor.
Chen Q
,
Schafer CT,
Mukherjee S,
Wang K,
Gustavsson M,
Fuller JR,
Tepper K,
Lamme TD,
Aydin Y,
Agrawal P,
Terashi G,
Yao XQ,
Kihara D,
Kossiakoff AA,
Handel TM,
Tesmer JJG
(2025) Nature , 643 , 280 - 287
,
Schafer CT,
Mukherjee S,
Wang K,
Gustavsson M,
Fuller JR,
Tepper K,
Lamme TD,
Aydin Y,
Agrawal P,
Terashi G,
Yao XQ,
Kihara D,
Kossiakoff AA,
Handel TM,
Tesmer JJG
(2025) Nature , 643 , 280 - 287
Grant Support:
- National Institutes of Health/National Cancer Institute (NIH/NCI): CA254402 (United States)
- National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): GM117372 (United States)
- National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID): AI161880 (United States)
- National Institutes of Health/National Cancer Institute (NIH/NCI): CA221289 (United States)
- National Institutes of Health/National Cancer Institute (NIH/NCI): CA023168 (United States)
- National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): GM137505 (United States)
- National Institutes of Health/National Heart, Lung, and Blood Institute (NIH/NHLBI): HL071818 (United States)
- National Institutes of Health/National Cancer Institute (NIH/NCI): CA023168 (United States)
- Walther Cancer Foundation: (United States)
- The Robertson Foundation: Irvington Postdoctoral Fellowship (United States)
- Villum Fonden: 00025326 (Denmark)
- Ralph W. and Grace M. Showalter Research Trust: 4480108 (United States)
