EMD-47520

Single-particle
4.3 Å
EMD-47520
3D View Gallery
Deposition: 25/10/2024
Map released: 25/06/2025
Last modified: 16/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-47520

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9e4y summary report (pdf.gz) Map-9e4y FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

GluA2-gamma2 complex bound to memantine, glutamate, and cyclothiazide

EMD-47520

Single-particle
4.3 Å
EMD-47520
3D View Gallery
Deposition: 25/10/2024
Map released: 25/06/2025
Last modified: 16/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Rattus norvegicus, Mus musculus
Sample: GluA2-TARPgamma2 Complex bound to memantine, glutamate, and cyclothiazide
Fitted models: 9e4y

Deposition Authors: Montano Romero A, Carrillo E , Jayaraman V , Twomey EC
Memantine inhibits calcium-permeable AMPA receptors.
Carrillo E , Montano Romero A, Gonzalez CU , Turcu AL , Vazquez S , Twomey EC , Jayaraman V
(2025) Nat Commun , 16 , 5576 - 5576
PUBMED: 40593487
DOI: doi:10.1038/s41467-025-60543-5
ISSN: 2041-1723