Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

EMD-47471

Composite map
Single-particle
3.5 Å
EMD-47471 Deposition: 23/10/2024
Map released: 19/03/2025
Last modified: 26/03/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-47471

Cryo-EM structure of yeast CMG helicase stalled at G4-containing DNA template, state 2

EMD-47471

Composite map
Single-particle
3.5 Å
EMD-47471 Deposition: 23/10/2024
Map released: 19/03/2025
Last modified: 26/03/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Saccharomyces cerevisiae W303, synthetic construct
Sample: Yeast CMG-CTM G4 stall state 2
Fitted models: 9e2x

Deposition Authors: Allwein B , Batra S , Remus D , Hite R
G-quadruplex-stalled eukaryotic replisome structure reveals helical inchworm DNA translocation.
Batra S , Allwein B , Kumar C, Devbhandari S, Bruning JG , Bahng S, Lee CM , Marians KJ, Hite RK , Remus D
(2025) Science , 387 , eadt1978 - eadt1978
PUBMED: 40048517
DOI: doi:10.1126/science.adt1978
ISSN: 1095-9203
ASTM: SCIEAS