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EMD-47260

Single-particle
2.76 Å
EMD-47260
3D View Gallery
Deposition: 09/10/2024
Map released: 12/03/2025
Last modified: 03/09/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-47260
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9dwq summary report (pdf.gz) Map and 9dwq FULL report (pdf.gz)
EMICSS annotations (xml)

PKD2 ion channel, F629S variant

EMD-47260

Single-particle
2.76 Å
EMD-47260
3D View Gallery
Deposition: 09/10/2024
Map released: 12/03/2025
Last modified: 03/09/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: PKD2 ion channel F629S variant protomer
Fitted models: 9dwq

Deposition Authors: Esarte Palomero O, DeCaen PG
Pathogenic variants in the polycystin pore helix cause distinct forms of channel dysfunction.
Palomero OE, Guadarrama E , DeCaen PG
(2025) PNAS , 122 , e2421362122 - e2421362122
PUBMED: 40504156
DOI: doi:10.1073/pnas.2421362122
ISSN: 1091-6490
ASTM: PNASA6