EMD-47174

Single-particle
2.9 Å
EMD-47174
3D View Gallery
Deposition: 04/10/2024
Map released: 19/11/2025
Last modified: 19/11/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-47174
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9dur summary report (pdf.gz) Map and 9dur FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM Structure of CRBN:dHTC1:ENL YEATS

EMD-47174

Single-particle
2.9 Å
EMD-47174
3D View Gallery
Deposition: 04/10/2024
Map released: 19/11/2025
Last modified: 19/11/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Ternary complex of dHTC1 induced DDB1dB/CRBN, ENL YEATS complex
Fitted models: 9dur

Deposition Authors: Cheong H, Hunkeler M, Fischer ES
High-throughput diversification of protein-ligand surfaces to discover chemical inducers of proximity.
Shaum JB, Munoz I Ordono M, Steen EA, Wenge DV, Cheong H, Hunkeler M, Bilotta EM, Rutter Z, Barta PA, Thornhill AM, Milosevich N, Hargis LM, Janowski J, Bishop TR, Carter TR, da Camara B, Hinterndorfer M, Dada L, He WJ, Offensperger F, Furihata H, Schweber SR, Hatton C, Wen Y, Cravatt BF, Engle KM, Donovan KA, Melillo B, Kitamura S, Ciulli A, Armstrong SA, Fischer ES, Winter GE, Erb MA
(2025) bioRxiv
PUBMED: 40950085
DOI: doi:10.1101/2024.09.30.615685
ISSN: 2692-8205