EMD-47156

Single-particle
2.87 Å
EMD-47156
3D View Gallery
Deposition: 01/10/2024
Map released: 27/11/2024
Last modified: 11/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-47156

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9dtq summary report (pdf.gz) Map-9dtq FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

The structure of HDAC2-CoREST in complex with KBTBD4R313PRR mutant

EMD-47156

Single-particle
2.87 Å
EMD-47156
3D View Gallery
Deposition: 01/10/2024
Map released: 27/11/2024
Last modified: 11/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: LHC-KBTBD4PRRmutant
Fitted models: 9dtq

Deposition Authors: Xie X , Liau B, Zheng N
Converging mechanism of UM171 and KBTBD4 neomorphic cancer mutations.
Xie X , Zhang O , Yeo MJR , Lee C , Tao R, Harry SA, Payne NC , Nam E, Paul L , Li Y , Kwok HS , Jiang H , Mao H, Hadley JL , Lin H, Batts M , Gosavi PM , D'Angiolella V , Cole PA , Mazitschek R , Northcott PA , Zheng N , Liau BB
(2025) Nature , 639 , 241 - 249
PUBMED: 39939763
DOI: doi:10.1038/s41586-024-08533-3
ISSN: 1476-4687
ASTM: NATUAS
Grant Support: