EMD-46960

Single-particle
3.3 Å
EMD-46960
3D View Gallery
Deposition: 09/09/2024
Map released: 15/10/2025
Last modified: 25/02/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-46960
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9dkk summary report (pdf.gz) Map and 9dkk FULL report (pdf.gz)
EMICSS annotations (xml)

Designed miniproteins potently inhibit and protect against MERS-CoV. MERS-CoV S in complex with miniprotein cb3_GGGSGGGS_SB175, linker 7 (Local refinement of two RBDs and 2 miniproteins)

EMD-46960

Single-particle
3.3 Å
EMD-46960
3D View Gallery
Deposition: 09/09/2024
Map released: 15/10/2025
Last modified: 25/02/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Middle East respiratory syndrome-related coronavirus, synthetic construct
Sample: MERS-CoV S in complex with miniprotein cb3_GGGSGGGS_SB175, linker 7 (Local refinement of two RBDs and 2 miniproteins)
Fitted models: 9dkk

Deposition Authors: Tortorici MA , Veesler D , Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Designed miniproteins potently inhibit and protect against MERS-CoV.
Ragotte RJ, Tortorici MA , Catanzaro NJ, Addetia A, Coventry B, Froggatt HM, Lee J, Stewart C, Brown JT, Goreshnik I, Sims JN, Milles LF, Wicky BIM, Glogl M, Gerben S, Kang A, Bera AK, Sharkey W, Schafer A, Harkema JR, Baric RS, Baker D, Veesler D
(2025) Cell Rep , 44 , 115760 - 115760
PUBMED: 40450691
DOI: doi:10.1016/j.celrep.2025.115760
ISSN: 2211-1247