EMD-46884
Q23.MD39 in Complex with Fabs from antibodies CH01 iGL and 35O22
EMD-46884
Single-particle3.35 Å
Deposition: 04/09/2024Map released: 17/12/2025
Last modified: 13/05/2026
Sample Organism:
Homo sapiens,
Human immunodeficiency virus 1
Sample: Q23.MD39 Env trimer in Complex with CH01 iGL and 35O22
Fitted models: 9dhw
Deposition Authors: Lin ZJ, Cui J, Du J, Habib R
,
Kulp D,
Pallesen J
Sample: Q23.MD39 Env trimer in Complex with CH01 iGL and 35O22
Fitted models: 9dhw
Deposition Authors: Lin ZJ, Cui J, Du J, Habib R
,
Kulp D,
Pallesen J
Deep mining of the human antibody repertoire identifies frequent and genetically diverse CDRH3 topologies targetable by vaccination.
Habib R ,
Solieva SO,
Lin ZJ,
Ghosh S,
Bayruns K,
Singh M,
Agostino CJ,
Tursi NJ,
Sowers KJ,
Huang J,
Roark RS,
Purwar M,
Park Y,
Ayyanathan K,
Li H,
Carey JW,
Kim A,
Park J,
McCanna ME,
Skelly AN,
Chokkalingam N,
Kriete S,
Shupin N,
Huynh A,
Walker S,
Sadeesh R,
Laenger N,
Du J,
Cui J,
Patel A,
Escolano A,
Kwong PD,
Shapiro L,
Bowman GR,
Hahn BH,
Shaw GM,
Weiner DB,
Pallesen J,
Kulp DW
(2026) PNAS , 123 , e2532810123 - e2532810123
,
Solieva SO,
Lin ZJ,
Ghosh S,
Bayruns K,
Singh M,
Agostino CJ,
Tursi NJ,
Sowers KJ,
Huang J,
Roark RS,
Purwar M,
Park Y,
Ayyanathan K,
Li H,
Carey JW,
Kim A,
Park J,
McCanna ME,
Skelly AN,
Chokkalingam N,
Kriete S,
Shupin N,
Huynh A,
Walker S,
Sadeesh R,
Laenger N,
Du J,
Cui J,
Patel A,
Escolano A,
Kwong PD,
Shapiro L,
Bowman GR,
Hahn BH,
Shaw GM,
Weiner DB,
Pallesen J,
Kulp DW
(2026) PNAS , 123 , e2532810123 - e2532810123
Grant Support: