EMD-46695

Single-particle
2.8 Å
EMD-46695
3D View Gallery
Deposition: 22/08/2024
Map released: 09/04/2025
Last modified: 23/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-46695

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9dao summary report (pdf.gz) Map-9dao FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

AlphaIIbbeta3 in fully-extended conformation in complex with R6H8 Fab

EMD-46695

Single-particle
2.8 Å
EMD-46695
3D View Gallery
Deposition: 22/08/2024
Map released: 09/04/2025
Last modified: 23/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Mus musculus
Sample: AlphaIIbbeta3 in fully-extended conformation in complex with R6H8 Fab
Fitted models: 9dao

Deposition Authors: Walz T, Coller BS , Wang JL, Buitrago L , Wang L, Li JH
An alpha IIb beta 3 ligand-mimetic murine monoclonal antibody that produces platelet activation by engaging the Fc gamma IIa receptor.
Wang J , Buitrago L , Wang L, Li J, Walz T, Coller BS
(2025) Blood Adv , 9 , 3518 - 3529
PUBMED: 40101235
DOI: doi:10.1182/bloodadvances.2024015368
ISSN: 2473-9537