EMD-46600

Single-particle
2.67 Å
EMD-46600
3D View Gallery
Deposition: 16/08/2024
Map released: 04/02/2026
Last modified: 11/02/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-46600
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9d72 summary report (pdf.gz) Map and 9d72 FULL report (pdf.gz)
EMICSS annotations (xml)

CryoEM structure of anti-MHC-I Fab M1/42 complex with H2-Dd

EMD-46600

Single-particle
2.67 Å
EMD-46600
3D View Gallery
Deposition: 16/08/2024
Map released: 04/02/2026
Last modified: 11/02/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Rattus norvegicus, Mus musculus, synthetic construct
Sample: Complex of Anti mouse Fab M1/42 and MHC-I H2-Dd
Fitted models: 9d72

Deposition Authors: Jiang J, Natarajan K, Margulies DH, Lei H, Huang R
Structural mechanism of anti-MHC-I antibody blocking of inhibitory NK cell receptors in tumor immunity.
Jiang J, Panda AK, Natarajan K, Lei H, Sharma S, Boyd LF, Towler RR, Chempati S, Ahmad J, Morton AJ, Lang ZC, Sun Y, Sgourakis N, Meier-Schellersheim M, Huang RK, Shevach EM, Margulies DH
(2026) Commun Biol
PUBMED: 41629525
DOI: doi:10.1038/s42003-026-09641-8
ISSN: 2399-3642