EMD-46593

Single-particle
2.1 Å
EMD-46593
3D View Gallery
Deposition: 14/08/2024
Map released: 30/10/2024
Last modified: 29/04/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-46593
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9d6c summary report (pdf.gz) Map and 9d6c FULL report (pdf.gz)
EMICSS annotations (xml)

Gag CA-SP1 immature lattice bound with Lenacapavir and Bevirimat from enveloped virus like particles

EMD-46593

Single-particle
2.1 Å
EMD-46593
3D View Gallery
Deposition: 14/08/2024
Map released: 30/10/2024
Last modified: 29/04/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Human immunodeficiency virus type 1 (NEW YORK-5 ISOLATE), Human immunodeficiency virus type 1 group M subtype B (isolate HXB2)
Sample: Human immunodeficiency virus type 1 (NEW YORK-5 ISOLATE)
Fitted models: 9d6c

Deposition Authors: Wu C , Meuser ME, Xiong Y
Distinct Target Site of Lenacapavir in Immature HIV-1 and Concurrent Binding with the Maturation Inhibitor Bevirimat.
Wu C , Meuser ME, Rey JS , Meshkin H, Yang R, Devarkar SC, Freniere C , Shi J, Aiken C, Perilla JR , Xiong Y
(2025) J Am Chem Soc , 147 , 42685 - 42700
PUBMED: 41198571
DOI: doi:10.1021/jacs.5c13735
ISSN: 1520-5126
ASTM: JACSAT