EMD-45982

Single-particle
3.34 Å
EMD-45982
3D View Gallery
Deposition: 31/07/2024
Map released: 13/11/2024
Last modified: 04/03/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-45982
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9cx9 summary report (pdf.gz) Map and 9cx9 FULL report (pdf.gz)
EMICSS annotations (xml)

Structure of SH3 domain of Src in complex with beta-arrestin 1

EMD-45982

Single-particle
3.34 Å
EMD-45982
3D View Gallery
Deposition: 31/07/2024
Map released: 13/11/2024
Last modified: 04/03/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Rattus norvegicus, Mus musculus, Homo sapiens, Gallus gallus
Sample: Beta-arrestin 1 bound to a G protein-coupled receptor phosphopeptide and antibody fragment Fab30 in complex with SH3 domain of Src
Fitted models: 9cx9

Deposition Authors: Pakharukova N, Bansia H, Lefkowitz RJ , des Georges A
Mechanism of beta-arrestin 1 mediated Src activation via Src SH3 domain revealed by cryo-electron microscopy.
Pakharukova N, Thomas BN , Bansia H, Li L, Bassford DK, Abzalimov RR , Kim J, Kahsai AW, Pani B , Xiao K , Ochakovski R, Liu S, Zhang X, Ahn S , des Georges A , Lefkowitz RJ
(2026) Nat Commun
PUBMED: 41720803
DOI: doi:10.1038/s41467-026-69884-1
ISSN: 2041-1723