Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!
EMD-45934
Structure of human full-length ancestral TRPV6 channel in Calmodulin-bound state
EMD-45934
Single-particle3.42 Å
Deposition: 26/07/2024Map released: 13/11/2024
Last modified: 04/06/2025
Sample Organism:
Homo sapiens
Sample: ancestral hTRPV6 tetramer in complex with Calmodulin
Fitted models: 9cui
Deposition Authors: Neuberger A
,
Nadezhdin KD,
Sobolevsky AI,
Sobolevsky AI
Sample: ancestral hTRPV6 tetramer in complex with Calmodulin
Fitted models: 9cui
Deposition Authors: Neuberger A
,
Nadezhdin KD,
Sobolevsky AI,
Sobolevsky AI
Structure-function analyses of human TRPV6 ancestral and derived haplotypes.
Neuberger A ,
Shalygin A,
Trofimov YA,
Veretenenko II ,
Nadezhdin KD,
Krylov NA,
Gudermann T,
Efremov RG,
Chubanov V ,
Sobolevsky AI
(2025) Structure , 33 , 91 - 103.e5
,
Shalygin A,
Trofimov YA,
Veretenenko II ,
Nadezhdin KD,
Krylov NA,
Gudermann T,
Efremov RG,
Chubanov V ,
Sobolevsky AI
(2025) Structure , 33 , 91 - 103.e5
Grant Support:
- National Institutes of Health/National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIH/NIAMS): R01 AR078814 (United States)
- National Institutes of Health/National Cancer Institute (NIH/NCI): R01 CA206573 (United States)
- National Institutes of Health/National Institute of Neurological Disorders and Stroke (NIH/NINDS): R01 NS083660 (United States)
- National Institutes of Health/National Institute of Neurological Disorders and Stroke (NIH/NINDS): R01 NS107253 (United States)
- German Research Foundation (DFG): 464295817 (Germany)