Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

EMD-45918

Single-particle
2.5 Å
EMD-45918
3D View Gallery
Deposition: 25/07/2024
Map released: 25/09/2024
Last modified: 25/09/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-45918
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9ctt summary report (pdf.gz) Map and 9ctt FULL report (pdf.gz)
EMICSS annotations (xml)

Best1 + GABA closed state

EMD-45918

Single-particle
2.5 Å
EMD-45918
3D View Gallery
Deposition: 25/07/2024
Map released: 25/09/2024
Last modified: 25/09/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: GABA-bound Homopentameric complex of Best1 anion channel in fully open fffff state
Fitted models: 9ctt

Deposition Authors: Owji AP, Kittredge A , Zhang Y , Yang T
GAD65 tunes the functions of Best1 as a GABA receptor and a neurotransmitter conducting channel.
Wang J , Owji AP, Kittredge A , Clark Z, Zhang Y , Yang T
(2024) Nat Commun , 15 , 8051 - 8051
PUBMED: 39277606
DOI: doi:10.1038/s41467-024-52039-5
ISSN: 2041-1723