EMD-45739

Single-particle
4.61 Å
EMD-45739
3D View Gallery
Deposition: 12/07/2024
Map released: 21/05/2025
Last modified: 08/10/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-45739

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9cm5 summary report (pdf.gz) Map-9cm5 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

CryoEM Strucuture of TcdB in complex with De Novo Minibinder fzd48

EMD-45739

Single-particle
4.61 Å
EMD-45739
3D View Gallery
Deposition: 12/07/2024
Map released: 21/05/2025
Last modified: 08/10/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Escherichia coli, synthetic construct, Clostridioides difficile
Sample: tcdB with de novo minibinder fzd48
Fitted models: 9cm5

Deposition Authors: Weidle C, Carr KD , Borst AJ
De novo design of potent inhibitors of clostridial family toxins.
Ragotte RJ , Liang H , Tam J, Miletic S, Berman JM , Palou R , Weidle C, Li Z, Glogl M , Beilhartz GL , Carr KD , Borst AJ , Coventry B, Wang X, Rubinstein JL , Tyers M, Schramek D, Melnyk RA , Baker D
(2025) PNAS , 122 , e2509329122 - e2509329122
PUBMED: 40982695
DOI: doi:10.1073/pnas.2509329122
ISSN: 1091-6490
ASTM: PNASA6
Grant Support: