EMD-45728

Single-particle
3.43 Å
EMD-45728
3D View Gallery
Deposition: 12/07/2024
Map released: 11/09/2024
Last modified: 14/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-45728

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9clp summary report (pdf.gz) Map-9clp FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Structure of ecarin from the venom of Kenyan saw-scaled viper in complex with the Fab of neutralizing antibody H11

EMD-45728

Single-particle
3.43 Å
EMD-45728
3D View Gallery
Deposition: 12/07/2024
Map released: 11/09/2024
Last modified: 14/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Echis pyramidum leakeyi, Echis carinatus
Sample: Ecarin in complex with neutralizing antibody H11
Fitted models: 9clp

Deposition Authors: Mindrebo JT, Lander GC
Importance of the Cysteine-Rich Domain of Snake Venom Prothrombin Activators: Insights Gained from Synthetic Neutralizing Antibodies.
Misson Mindrebo LE , Mindrebo JT, Tran Q , Wilkinson MC , Smith JM , Verma M, Casewell NR , Lander GC , Jardine JG
(2024) Toxins , 16
PUBMED: 39195771
DOI: doi:10.3390/toxins16080361
ISSN: 2072-6651