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EMD-45601

Single-particle
3.54 Å
EMD-45601
3D View Gallery
Deposition: 02/07/2024
Map released: 08/01/2025
Last modified: 19/03/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-45601
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9cht summary report (pdf.gz) Map and 9cht FULL report (pdf.gz)
EMICSS annotations (xml)

Human E3 ligase E6AP in complex with HPV16-E6 and p53

EMD-45601

Single-particle
3.54 Å
EMD-45601
3D View Gallery
Deposition: 02/07/2024
Map released: 08/01/2025
Last modified: 19/03/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Human papillomavirus 16
Sample: Ternary complex of E6AP with viral factor E6 and neosubstrate p53
Fitted models: 9cht

Deposition Authors: Kenny S , Das C
Structure of E6AP in complex with HPV16-E6 and p53 reveals a novel ordered domain important for E3 ligase activation.
Kenny S , Iyer S, Gabel CA, Tegenfeldt N, DeMarco AG, Hall MC, Chang L, Davisson VJ , Pol SV, Das C
(2025) Structure , 33 , 504 - 516.e4
PUBMED: 39818213
DOI: doi:10.1016/j.str.2024.12.013
ISSN: 0969-2126
ASTM: STRUE6