EMD-45456

Single-particle
3.17 Å
EMD-45456
3D View Gallery
Deposition: 23/06/2024
Map released: 02/07/2025
Last modified: 02/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-45456
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9ccs summary report (pdf.gz) Map and 9ccs FULL report (pdf.gz)
EMICSS annotations (xml)

CryoEM Structure of Escherichia coli FimCH in complex with 2H04 Fab

EMD-45456

Single-particle
3.17 Å
EMD-45456
3D View Gallery
Deposition: 23/06/2024
Map released: 02/07/2025
Last modified: 02/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Mus musculus, Escherichia coli, Escherichia coli UTI89
Sample: Complex of FimCH with 2H04 Fab
Fitted models: 9ccs

Deposition Authors: Lopatto EDB , Hultgren SJ
Monoclonal antibodies targeting the FimH adhesin protect against uropathogenic E. coli UTI.
Lopatto EDB , Santiago-Borges JM , Sanick DA , Malladi SK , Azimzadeh PN , Timm MW , Fox IF, Schmitz AJ , Turner JS , Sayed Ahmed SM, Ortinau L , Gualberto NC , Pinkner JS , Dodson KW, Ellebedy AH , Kau AL , Hultgren SJ
(2025) Sci Adv , 11 , eadw0698 - eadw0698
PUBMED: 40540557
DOI: doi:10.1126/sciadv.adw0698
ISSN: 2375-2548